Public knowledge infrastructure · Established 2000
The world’s knowledge about HIV—connected, verified and accessible.
Explore HIV prevention, testing, treatment, clinical trials, global data, scientific research, institutions, and the continuing search for durable remission and a cure.
Popular:What is HIV?What does undetectable mean?HIV testing after a recent exposureCurrent HIV prevention optionsHIV clinical trialsLatest cure and remission research
SSource-traceablePPlain languageAAcademic referencesGGlobal contextRPeriodically reviewed
Living evidence systemOpen methods
CLAIM RECORD · ARC-CLM-001Every conclusion stays connected to its evidence.
Public explanation, source record, guideline, trial, dataset and update history remain visible together.
EstablishedLast checked 18 Aug 2026
22Verified sources
03Guidelines
09Primary studies
04Standards
Time-sensitive information
Concerned about a recent possible exposure?
Some preventive options are time sensitive. Find authoritative local information and appropriate professional services.
Choose a pathway
Find the right starting point
The facts stay the same; the route and level of explanation adapt to what you need.
I am learning about HIV
→Clear foundations, definitions and myth correction.
I need prevention or testing
→Options, test types and time-sensitive pathways.
I am living with HIV
→Treatment, health, rights and daily life.
I am supporting someone
→Respectful guidance for partners, families and caregivers.
I am a healthcare professional
→Guidelines, evidence summaries and clinical sources.
I am a researcher
→Literature, trials, datasets, gaps and collaborators.
I work in public health or policy
→Data, policy comparisons and implementation evidence.
I am a student, educator or journalist
→Learning paths, citations, timelines and explainers.
Global data snapshot
The 2025 epidemic in context
Estimates include uncertainty. Source: UNAIDS 2026 epidemiological estimates, released 27 July 2026.
Reference year 2025 · Reporting date 27 Jul 2026 · Modelled estimatesView source, methods and downloadable data
Complete public index
Explore the Center
Eleven connected chapters move from essential knowledge to advanced research, policy, data, people and education.
0148 topics
Understand HIV
Biology, transmission, history, myths and terminology.
Explore chapter0239 topics
Prevention and Testing
Prevention choices, test technologies, rights and urgent guidance.
Explore chapter0382 topics
Treatment and Living Well
Treatment, monitoring, long-term health, rights and daily life.
Explore chapter0412 source types
Research Library
Source records, systematic reviews, guidelines, datasets and integrity notices.
Explore chapter058 trial views
Clinical Trials
Registry-linked trials by purpose, phase, country and recruitment status.
Explore chapter06195 country pathways
Global Data and Countries
Country profiles, indicators, sources, uncertainty and methodology.
Explore chapter076 pipelines
HIV Research and Development
Prevention, treatment, vaccine, cure, diagnostics and implementation pipelines.
Explore chapter089 collections
Policy, Programs and Rights
Strategies, laws, rights, program implementation and case studies.
Explore chapter099 directories
People and Institutions
Researchers, institutions, laboratories, networks, funders and community groups.
Explore chapter108 resource types
Education and Resources
Learning paths, teaching tools, visual explainers and downloads.
Explore chapter11Open governance
About the Center
Mission, governance, evidence methods, corrections, ethics, privacy and public promise.
Explore chapterAll public-health topics
A complete visual knowledge index
Every listed topic below is a visible, permanent link. Use the chapter search or open each evidence record directly.
HIV fundamentals
Understand HIV
Learn what HIV is, how it affects the immune system, how transmission occurs, what does not transmit HIV, and how scientific knowledge has developed.
Explore all understand hiv5 major sections · 48 indexed topics
FoundationsThe essential biology, terminology and progression of HIV infection.14 topics
TransmissionEvidence-based explanations of transmission routes and the factors that influence risk.8 topics
What does not transmit HIVClear, respectful answers to common fears about everyday contact.8 topics
HistoryThe scientific, medical, social and community history of the global HIV response.12 topics
Terminology and glossaryMedical, scientific, public-health and community terminology with sources and usage notes.6 topics
Prevent, test and act early
Prevention and Testing
Explore established and emerging prevention methods, understand HIV testing technologies, and find time-sensitive guidance after a possible exposure.
Explore all prevention and testing3 major sections · 35 indexed topics
Combination preventionMedical, behavioral, community and structural approaches work together.15 topics
Medical prevention
Barrier and sexual-health prevention
Harm reduction and blood safety
Pregnancy and community prevention
Testing Knowledge CenterHow tests work, when they may detect infection, and how results are confirmed.15 topics
Types of HIV tests
Testing in specific contexts
Understanding results
Rights and next steps
Possible recent exposureTime-sensitive professional assessment may be appropriate after a possible recent exposure.5 topics
- Urgent-exposure guidance
- Find official guidance
- Find relevant services
- Occupational exposure guidance
- Privacy and recent-exposure searches
Jurisdiction matters. Time-sensitive guidance must show its issuing authority, location and review date. This portal never asks for or stores an exposure history.
Treatment, health and everyday life
Treatment and Living Well
Understand treatment, monitoring, long-term health, opportunistic infections, life across different ages, and the practical realities of living with HIV.
Explore all treatment and living well6 major sections · 77 indexed topics
Starting treatmentWhat to understand when entering or returning to HIV care.9 topics
Antiretroviral therapyHow treatment works, how regimens are selected, and what affects treatment success.13 topics
Understanding treatment
Maintaining treatment
Changing or accessing treatment
Living-guideline notice. Treatment guidance is dated and jurisdiction specific. Records show the issuing authority, intended population, current status and what changed.
MonitoringTests and follow-up used to understand treatment response and long-term health.9 topics
Opportunistic infections and advanced diseaseEvidence-based indexes for conditions associated with advanced immune suppression.11 topics
Living well across the lifespanHealth, wellbeing and care needs across ages and stages of life.20 topics
Reproductive and sexual health
Mental and behavioral health
Long-term physical health
Supportive care
Daily lifePractical information about relationships, privacy, work, travel, family and social life.15 topics
Relationships and family
Work, education and housing
Travel and migration
Evidence, data and progress
From a claim to the complete scientific record
Research is organized by relationships—not simply placed in a list of papers.
CLAIMWhat does the evidence establish?Public answer · technical record · uncertainty
StudiesDesign · population · resultsTrialsRegistry · status · outcomesGuidelinesAuthority · date · jurisdictionPeopleAuthors · institutions · fundersDataMethods · uncertainty · licenseIntegrityCorrections · retractions · updatesResearch Library
- Search scientific research
- Browse systematic reviews
- Browse clinical studies
- Browse datasets
- Browse guidelines
- Corrected and retracted research
- Research by country
- Research by institution
Clinical Trials
- Recruiting trials
- Prevention trials
- Treatment trials
- Vaccine trials
- Cure and remission trials
- Diagnostic trials
- Trials by country
- Trials with published results
Global Data and Countries
- Global indicators
- Country search
- Regional comparisons
- Treatment indicators
- Prevention indicators
- Testing indicators
- Viral-suppression indicators
- Policy and law indicators
HIV R&D
- Prevention pipeline
- Treatment pipeline
- Vaccine pipeline
- Cure and remission pipeline
- Diagnostics pipeline
- Implementation science
- Open research questions
- Reproducibility center
Policy, Programs and Rights
- National strategies
- Testing policies
- Treatment policies
- Prevention policies
- Human-rights resources
- Case studies
- Laws affecting people living with HIV
- Stigma and discrimination
People and Institutions
- Researchers
- Research institutions
- Hospitals
- Laboratories
- Universities
- Government bodies
- International organizations
- Community organizations
- Funders
- Research networks
Education and Resources
- Public learning paths
- Professional resources
- Teaching materials
- Reading lists
- Visual explainers
- Glossary
- Frequently asked questions
- Misinformation and myth correction
- Downloadable resources
- Historical materials
HIV research & development
Track progress without overstating promise
Twelve evidence-dated directions span prevention, long-acting treatment, vaccines, remission science, gene and cell therapy, reservoir measurement and equitable delivery.
Explore the complete R&D portfolio01
Prevention · EstablishedTwice-yearly injectable PrEP
→02Treatment · EstablishedLong-acting treatment platforms
→03Vaccine · Early clinicalGermline-targeting and sequential HIV vaccines
→04Cure and remission · Clinical researchBroadly neutralizing antibody combinations
→05Cure and remission · Clinical researchTherapeutic vaccines and immune education
→06Cure and remission · Clinical researchLatency reversal and reservoir clearance
→Dated and source-linked
Latest evidence and important updates
Updates are classified by evidence status. Early findings are never presented as breakthroughs by default.
WHO consolidated HIV service-delivery guidance
A new consolidated edition brings together person-centred, integrated and equitable service-delivery recommendations.
Guideline supportedWorld Health Organization
Open source record UNAIDS releases 2025 global estimates
Country reporting and modelled estimates include uncertainty ranges for prevalence, treatment, incidence and mortality.
Authoritative datasetUNAIDS
Open source record WHO updates HIV clinical-management recommendations
The update covers antiretroviral therapy, vertical transmission and tuberculosis prevention for people living with HIV.
Guideline supportedWorld Health Organization
Open source record NIH reviews the basics of HIV prevention
A public fact sheet explains testing, PrEP, PEP, condoms, treatment as prevention and avoiding shared injection equipment.
Reviewed public guidanceNIH HIVinfo
Open source record Corrections and retractions remain part of the record
Research records retain correction, expression-of-concern and retraction status rather than silently disappearing.
Integrity policyCenter editorial method
Open source record Trial records should connect registration to results
Registry inclusion does not establish effectiveness or endorsement; status and results require source verification.
Source recordClinicalTrials.gov and WHO ICTRP
Open source record Terminology and glossary
Understand the language of HIV
Each term supports a public definition, technical definition, pronunciation, synonyms, usage notes, related concepts, references and translations.
Useful without surveillance
Public tools and free downloads
These tools run without an account. No health status, exposure history or search profile is sent to the Center.
Research tool
Source appraisal checklist
Use six practical checks before relying on a medical or research claim. This is not a numerical truth score.
0 of 6 checks completedUnanswered checks identify what to verify next.
No answers are transmitted or stored.Privacy-first finder
Find official guidance by region
Select a broad region on this device. For a possible recent exposure, seek qualified local assessment promptly.
Global guidance and links to WHO regional offices.Open WHO HIV guidance
Your selection stays in this browser and is not submitted to the Center.CSV · FreeEvidence appraisal worksheet
Six checks for source quality, dates, population, limitations, funding and integrity.
TXT · FreeQuestions for a healthcare visit
A private printable prompt sheet for discussing tests, treatment and guidance.
TXT · FreeHIV knowledge starter guide
A plain-language pathway through HIV foundations, prevention, testing, treatment and evidence.
JSON · FreeResearch source record template
A provenance-first schema for studies, trials, guidelines, datasets and integrity status.
CSV · FreeClinical trial record review checklist
A structured review of registration, design, recruitment, outcomes, results and integrity.
CSV · FreeHIV research question planner
A PICO-aware planning sheet for population, intervention, comparator, outcomes, equity and feasibility.
TXT · FreePrivacy-first health website checklist
Practical checks for minimizing sensitive data, tracking, forms, embeds and search exposure.
TXT · FreeSource citation and update guide
A concise guide to identifiers, versions, access dates, corrections and change notes.
How trust is earned
Sources remain more visible than summaries.
We will never hide uncertainty, confuse a hypothesis with a fact, promote a product because its manufacturer funds us, or separate a conclusion from its sources.